New Study On Prevention Of Transfer Of HIV

New Study On Prevention Of Transfer Of HIV.
An antiviral antidepressant may worker nurture injection drug users from HIV infection, a experimental study finds. The study of more than 2400 injection knock out users recruited at 17 drug treatment clinics in Thailand found that ordinary tablets of tenofovir reduced the risk of HIV infection by nearly 49 percent, compared to out of a job placebo pills zetaclear. One first-rate said an intervention to help shield injection cure-all users from HIV - the virus that causes AIDS - is much needed.

And "This is an substantial study that opens up an additional alternative for preventing HIV in a hard-to-reach population," said Dr Joseph McGowan, medical skipper at the Center for AIDS Research and Treatment at North Shore University Hospital in Manhasset, NY. He illustrious that "HIV infections extend to transpire at high rates, with over 2,5 million worldwide and 50000 uncharted infections in the US each year male size. This is in the face widespread knowledge about HIV infection and the way it is spread, through unprotected gender and sharing needles for injecting drugs".

The participants included in the untrodden study were followed for an average of four years. During that time, 17 of the more than 1200 patients taking tenofovir became infected with HIV, compared with 33 of an like mass of patients taking a placebo, according to the investigation published online June 12, 2013 in The Lancet. Further analyses of the results showed that the watchful effect of tenofovir was highest to each those who most closely followed the drug's prescribed regimen.

In this group, the peril of HIV infection was reduced by more than 70 percent, said consider leaders Dr Kachit Choopanya and Dr Michael Martin, first of clinical research for the Thailand Ministry of Public Health-US Centers for Disease Control and Prevention Collaboration. Prior scrutinize has shown that counter-agent use of antiviral drugs cuts the jeopardy of sexual transmission of HIV in both heterosexual couples and men who have making love with men, and also reduces mother-to-child transmission of HIV.

But this is the first off study to show that this approach might also be effective among injection stimulant users. Worldwide, injection drug use is believed to cause one in 10 different HIV infections. But rates of infection associated with injection hallucinogen use are far higher in some areas of the world, such as eastern Europe and main Asia.

In these regions, up to 80 percent of reborn HIV infections are caused by injection drug use. According to McGowan, tenofovir is no "silver bullet" that would, on its own, reject the endanger of HIV infection for drug abusers. But it could be a clarification ingredient in reducing the odds.

So "Adoption of this strategy, not as a stand-alone, but in conjunction with needle exchange, counseling, opiate substitution, venereal bear out and mental health therapy may enable us to get winning of this expanding epidemic". He added that the participants in the study were also provided with what's known as "directly observed therapy," where the downer is administered under the accordance of a health care worker.

Services like this, along with monthly HIV testing and condom distribution, might not chance in "real life" remedying situations so outcomes might not be as good as in this clinical trial. Another whiz agreed that adherence to tenofovir group therapy is key to success here. Tenofovir "accumulates slowly in the body, making the lawsuit for adherence - which is strongly associated with the efficacy of the drug," said Victoria Richards, helpmate professor of medical sciences at the Frank H Netter MD School of Medicine at Quinnipiac University, in Hamden, Conn.