Another Genetic Cause Of Alzheimer's Disease

Another Genetic Cause Of Alzheimer's Disease.
Researchers have discovered that the evolution of a gene associated with premature debut Alzheimer's may block a key recycling process needed for brain cell survival - a finding that points the modus operandi to possible treatment for the disease factor. When it's working properly, this gene - called presenilin 1 (PS1) - performs a major house-cleaning assistance by helping sagacity cells digest unwanted, damaged and potentially toxic proteins.

But in its mutated form, the gene fails to ease cells recycle these implied toxins, suggesting an explanation for the damage to the percipience characteristic of Alzheimer's disease learn more. "We believe we have identified the starring mechanism by which mutations of PS1 cause the most common genetic arrangement of Alzheimer's disease," study co-author Dr Ralph A Nixon, professor in the departments of psychiatry and cubicle biology as well as overseer of NYU's Center of Excellence on Brain Aging and the Silberstein Alzheimer's Institute, said in a university advice release.

And "Presently, no efficient treatment exists to either slow or prevent the progression of Alzheimer's disease," added Nixon, also maestro of the Center for Dementia Research at the Nathan S Kline Institute for Psychiatric Research in New York City. "This development has the future of identifying such a treatment".