Morphine Can Protect The Brains Of People Suffering From HIV Infection

Morphine Can Protect The Brains Of People Suffering From HIV Infection.
The sedative morphine may remedy keep safe against HIV-associated dementia, says a changed study neosize xl plus. Georgetown University Medical Center researchers found that morphine protected rat neurons from HIV toxicity, a determining that could assume command to the development of new drugs to treat occupy with HIV-related dementia, which causes depression, anxiety and physical and bonkers problems.

So "We believe that morphine may be neuroprotective in a subset of consumers infected with HIV," lead investigator Italo Mocchetti, a professor of neuroscience, said in a Georgetown message release. He and his colleagues conducted the examine because they knew that some people with HIV who are heroin users never increase HIV brain dementia plus size aunty ki story. Morphine is equivalent to heroin.

In their tests on rats, the researchers found that morphine triggers sagacity cells called astrocytes to produce a protein called CCL5, which activates factors that terminate HIV infection in inoculated cells. CCL5 "is known to be important in blood, but we didn't comprehend it is secreted in the brain. Our hypothesis is that it is in the percipience to prevent neurons from dying".

The study was to be presented at the annual congregation of the Society of NeuroImmune Pharmacology, April 13 to 17 in Manhattan Beach, Calif. "Ideally, we can use this info to develop a morphine-like add to that does not have the typical dependency and tolerance issues that morphine has".

Austrian Scientists Have Determined The Effect Of Morphine On Blood Coagulation

Austrian Scientists Have Determined The Effect Of Morphine On Blood Coagulation.
Morphine appears to lessen the effectiveness of the commonly second-hand blood-thinning medicine Plavix, which could hold up emergency-room efforts to treat heart set victims, Austrian researchers report. The finding could fabricate serious dilemmas in the ER, where doctors have to weigh a nerve patient's intense pain against the need to break up and prevent blood clots, said Dr Deepak Bhatt, governmental overseer of interventional cardiovascular programs at Brigham and Women's Hospital Heart and Vascular Center, in Boston vito viga. "If a persistent is having crushing sincerity pain, you can't just tell them to tough it out, and morphine is the most commonly in use medication in that situation," said Bhatt, who was not affected in the study.

And "Giving them morphine is the humane whatsis to do, but it could also create delays in care". Doctors will have to be particularly painstaking if a heart attack patient needs to have a stent implanted, he said. Blood thinners are essential in preventing blood clots from forming around the stent sildenafilrx.net. "If that setting is unfolding, it requires a young bit of extra thought on the part of the physician whether they want to give that congested slug of morphine or not," Bhatt said.

About half of the 600000 stent procedures that ferry place in the United States each year develop as the result of a heart attack, angina or other on the qui vive coronary syndrome, he said. The Austrian researchers focused on 24 in good people who received either a dose of Plavix with an injection of morphine or a placebo drug. Morphine delayed the faculty of Plavix (clopidogrel) to unplentiful a patient's blood by an average of two hours, the researchers said.