Treatment Of Diabetes Is Different For Men And Women

Treatment Of Diabetes Is Different For Men And Women.
Widely old diabetes drugs have distinguishable gear on men's and women's hearts, a reborn study suggests. Researchers examined how three commonly prescribed treatments for specimen 2 diabetes affected 78 patients who were divided into three groups. One body took metformin alone, the two shakes group took metformin supplementary rosiglitazone (sold under the brand name Avandia) and the third party took metformin plus Lovaza, a type of fish oil bda injection for breast. Metformin reduces blood sugar work by the liver and improves insulin sensitivity.

Rosiglitazone also improves insulin over-sensitivity and moves unchained fatty acids out of the blood. Lovaza lowers blood levels of another genre of fat called triglycerides. The researchers found that the drugs had very separate and sometimes opposite effects on the hearts of men and women, even as the drugs controlled blood sugar equally well in both genders enhancement. The learning appears in the December children of the American Journal of Physiology - Heart and Circulatory Physiology.

Although metformin had sheer understanding effects in women, it caused the soul metabolism of men to burn less sugar and more fats. Chronic raging of fat by the heart results in harmful changes that can outstrip to heart failure, said the researchers, from the Washington University School of Medicine in St Louis. "Instead of making ticker metabolism more regular in men, metformin alone made it worse, looking even more approve of a diabetic heart," study ranking author Dr Robert Gropler said in a university story release.

And "But in women, metformin had the desired effect - lowering fleshy metabolism and increasing glucose perceptiveness by the heart". Taking either rosiglitazone or Lovaza with metformin seemed to tone down some of the negative heart effects of metformin alone in men. Taking rosiglitazone in counting up to metformin further improved women's callousness metabolism, compared to taking metformin alone.

The addition of Lovaza to metformin did not have a hard-nosed effect either way for men or women, the researchers said. "Our swatting suggests that we need to better define which therapies are optimal for women with diabetes and which ones are optimal for men," said Gropler, a professor of radiology. The swat did not, however, corroborate a cause-and-effect element between the drug combinations and basics changes hgh hardware. It showed only an association.