Omega-3 Does Not Prevent Atrial Fibrillation

Omega-3 Does Not Prevent Atrial Fibrillation.
Omega-3 fatty acid supplements don't lowered back on recurrences of atrial fibrillation, a paradigm of extraordinary heartbeat that can cause stroke, unfamiliar research suggests. "We now have definitive data that they don't pan out for most patients with AF atrial fibrillation ," said Dr Peter R Kowey, induce creator of a study appearing in the Dec 1, 2010 issue of the Journal of the American Medical Association that is also scheduled to be presented Monday at the American Heart Association's annual joining in Chicago. "Although we can't evict the chance of efficacy in sicker AF patients, it would be agonizing to believe that it would work in that population and not in healthier patients venda penis enlargement muthi. So for expedient purposes, yes, this is the end of the line in AF".

This study, the largest of its kind, looked at patients with AF who were otherwise healthy. "We cannot contemplate there is any convincing indication of a role for omega-3 in the prevention of atrial fibrillation," added Dr Ranjit Suri, number one of the Electrophysiology Service and Cardiac Arrhythmia Center at Lenox Hill Hospital in New York City, who was not labyrinthine with the trial enlargement. The learning was funded by GlaxoSmithKline.

Omega-3 fatty acids, which are found in fatty fish such as salmon and albacore tuna, had showed some give indication of in preventing fundamentals plague in earlier trials. Of the total 663 outpatient participants, 542 had paroxysmal atrial fibrillation, which appears all of a sudden and resolves on its own, and 121 had fixed atrial fibrillation, which needs treatment.

Participants were randomized to sustain either a placebo or 8 grams of omega-3 supplements ordinary for the first week, followed by 4 grams a age for the remaining 23 weeks of the trial. The doses hand-me-down in the study are available only by prescription and are "higher than doses once published in studies," said Dr Robert Block, a cardiologist and subsidiary professor of community and preventive medicament at the University of Rochester Medical Center.

At the end of six months, 46 percent of those in the placebo heap and 52 percent of those taking omega-3 supplements knowledgeable recurrences. The numbers of paroxysmal AF patients in the placebo and remedying groups who had AF recurrences were about selfsame (48 percent and 52 percent, respectively), the investigators found.

In patients with non-stop AF, more patients in the omega-3 arm had recurrences than in the placebo conglomeration (50 percent and 33 percent, respectively). But experts haven't ruled out a accomplishable duty for omega-3 in other types of patients, such as those with heart failure. "Our information do not speak to other cardiac indications," said Kowey, who is president of the Main Line Health Heart Center and a professor of nostrum and clinical pharmacology at Jefferson Medical College in Philadelphia.

So "There has been conflicting details there as well and a pure need for definitive studies for example ours in those indications. Omega-3 may be helpful in patients with serious triglycerides and bad overall cholesterol profiles or people horizontal to electric storms in the heart who are at risk of sudden death". Block recommends that patients with cardiovascular blight eat two servings of flattering fish weekly, or three over-the-counter omega-3 capsules a day vigora. In those with no cardiovascular disease, "there is no serviceable exhaustive benefit," but they still might also want to eat fish regularly.