Alzheimer's Disease Is Associated With A High Blood Pressure

Alzheimer's Disease Is Associated With A High Blood Pressure.
People distress from cardiovascular blight who have lower-than-normal blood tension may face a higher imperil of brain atrophy - the death of brain cells or connections between percipience cells, Dutch researchers report June 2013. Such leader atrophy can lead to Alzheimer's condition or dementia in these patients breastactives. In contrast, similar patients with strong blood pressure can slow brain atrophy by lowering their blood pressure, the researchers added.

Blood weight is measured using two readings. The uppermost number, called systolic pressure, gauges the prevail upon of blood moving through arteries. The bottom number, called diastolic pressure, measures the urge in the arteries between heartbeats vigrx plus. Normal blood arm for adults is less than 120/80, according to the US National Heart, Lung, and Blood Institute.

For the study, 70 to 90 was considered rational diastolic blood pressure, while under 70 was considered low. "Our matter might suggest that patients with cardiovascular c murrain pretend a subgroup within the general population in whom low diastolic blood strength might be harmful," said researcher Dr Majon Muller, an epidemiologist and geriatrician at VU University Medical Center in Amsterdam.

On the other hand, lowering blood coercion in males and females with high-class blood pressure might slow brain atrophy. "Our findings could evidence that blood pressure lowering is good in patients with higher blood pressure levels, but one should be cautious with further blood pressing lowering in patients who already have low diastolic blood pressure".

The blast was published in the June 10 online print run of JAMA Neurology. A US expert noted the complex junk of blood pressure levels on the brain. "High blood bring pressure to bear has been shown to increase the risk of vascular brain lesions and discernment atrophy. Trials of blood pressure lowering in patients with hypertension have shown reduced peril of brain lesions," said Dr Gregg Fonarow, a professor of cardiology at the University of California, Los Angeles, and a spokesman for the American Heart Association.

However, in patients with hypertension, the relation between the levels of systolic and diastolic blood press and planner atrophy has been less clear. This young contemplate suggests that low diastolic blood pressure levels were associated with intellect atrophy regardless of blood pressure levels after patients developed dementia. "These findings suggest that while care and supervise of high blood pressure is very important for brain and cardiovascular health, counsel is needed in patients who have low diastolic blood stress levels".

To see what changes blood pressure would earn in the progression of brain atrophy, Muller's group studied 663 patients who suffered from verve disease, cardiovascular disease, non-essential artery disease or abdominal aortic aneurysm. The undistinguished age of participants was 57 and most were men. People whose diastolic blood intimidation was below 70 had more brain atrophy over time, the boning up found.

For people with higher-than-normal blood pressure, genius atrophy decreased when their blood pressure did. When blood crushing rose, however, atrophy increased. Another expert, Dr Sam Gandy, accomplice director of the Mount Sinai Alzheimer's Disease Research Center in New York City, said that the find "is an significant cautionary tale".

This implies that one must shape the approach to the individual patient. Correction of hypertension is helpful, but reducing blood inducement in patients with run-of-the-mill blood pressure is risky and complicated" fatburning. Although the learn found an association between low diastolic blood pressure and the risk of developing intelligence atrophy for people with artery disease, it did not establish a cause-and-effect relationship.