понедельник, 1 июня 2015 г.

Surgery to treat rectal cancer

Surgery to treat rectal cancer.
For many rectal cancer patients, the thought of surgery is a worrisome reality, given that the functioning can significantly mar both bowel and sexual function. However, a strange study reveals that some cancer patients may fare just as well by forgoing surgery in favor of chemotherapy/radiation and "watchful waiting". The discovery is based on a look over of data from 145 rectal cancer patients, all of whom had been diagnosed with grade I, II or III disease revitol. All had chemotherapy and radiation.

But about half had surgery while the others staved off the mode in favor of rigorous tracking of their condition course - sometimes called "watchful waiting review. We assume that our results will encourage more doctors to consider this 'watch-and-wait' approach in patients with clinical undiminished response as an alternative to immediate rectal surgery, at least for some patients," chief study author Dr Philip Paty said in a word release from the American Society of Clinical Oncology (ASCO).

So "From my experience, most patients are pleased to assent some risk to defer rectal surgery in expectancy of avoiding major surgery and preserving rectal function," said Paty, a surgical oncologist at the Memorial Sloan-Kettering Cancer Center in New York City. The findings are to be presented Monday at the Gastrointestinal Cancers Symposium in San Francisco. ASCO is one of four organizations sponsoring the symposium. Research presented at medical meetings should be viewed as or technical prodromal until published in a peer-reviewed journal.

The boning up authors said that the typeface of patients who would most conceivable do well without closest surgery are the up to 50 percent of tier I patients whose tumors typically vanish totally following initial chemotherapy/radiation treatment. That reckon hovers at between 30 percent and 40 percent centre of stage II and III patients. The untrodden investigation looked at the experience of rectal cancer patients who were treated between 2006 and 2014 at Memorial Sloan-Kettering.

While all the patients had masterly culminate tumor regression following chemotherapy/radiation, only some underwent pressing rectal surgery. The other 73 patients were instead followed with "watchful waiting," which twisted follow-up exams every few months. Ultimately, nearly three-quarters of the non-surgery gather remained cancer-free approximately four years later, while about one leniency had to undergo surgery to treat tumor recurrence small red dots on skin. Overall, the four-year survival measure was 91 percent in the no-surgery bundle vs 95 percent in the surgery group.

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